Chihuahuas (definite introduction)
Some dogs still contract infectious diseases after being vaccinated on time, which makes many parents wonder whether the pet hospital is giving fake vaccines or outdated vaccines, but we don’t have it either. These possibilities can be eliminated, but there are also certain explanations for immune failure.
Reasons for immune failure
1. Genetic factors: The immune response of the animal body to vaccine crosses is controlled to a certain extent by genetic factors. There are many types of dogs, and the immune response They are all different, and even dogs of different breeds do not have the same immune response to a wide range of vaccines. Some dogs may even have genetic immune defects, leading to immune failure.
2. Maternal antibody disruption: This is one of the most common factors for immune failure. A certain level of maternal antibodies is extremely important in protecting puppies from early exposure to infectious diseases. However, due to the differences in the individual immune responses of breeding dogs and the differences in the vaccines used in breeding dogs (there are also large differences in the titers of maternal antibodies developed), maternal antibody levels in puppies with different origins are complex and uneven. If all puppies are vaccinated at the same age, puppies with too high maternal antibodies may disrupt the immune response of the vaccine, while puppies with too low maternal antibodies may be susceptible to infectious diseases when they are vaccinated. Obliterate the receptive period, thereby causing immune failure. Even if puppies from different breed bitches have different maternal antibody titers, they may not be completely consistent. If fixed first vaccination steps are taken, it will also disrupt the immune response of the vaccine and lead to immune failure.
3. Nutritional factors: Antibodies enter the body and produce different levels of immune responses - cellular immunity and humoral immunity, both of which require certain nutrients. Lack of or insufficient nutrients, especially vitamins A, D, B, E and various trace elements and full-price proteins, will affect the production speed or quantity of immune antibodies, thereby leading to delayed immune response or immune response. Ability decline leads to immune failure.
Insufficient immunization frequency, insufficient immunization dose, improper vaccination route, and other reasons may lead to immunity failure.
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